GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs8078723 | 1 | rs3826331 | chr17:38150492 | ZPBP2 | chr17:38024455-38034144:+ | 0.22 | 4.06 | 6.02E-5 | Neutrophil count;White blood cell count;C-reactive protein and white blood cell count |
| BLCA | cis | rs60843830 | 1 | rs3828165 | chr2:220889 | SH3YL1 | chr2:218138-264810:- | -0.45 | -11.84 | 9.03E-28 | Spherical equivalent (joint main effects and education interaction) |
| BLCA | cis | rs2243480 | 1 | rs383402 | chr7:65586653 | CCT6P1 | chr7:65216092-65228661:+ | -0.31 | -4.62 | 5.31E-6 | Diabetic kidney disease |
| BLCA | cis | rs10935120 | 1 | rs3846055 | chr3:134203973 | ANAPC13 | chr3:134196547-134204865:- | 0.51 | 8.16 | 4.83E-15 | Height |
| BLCA | cis | rs10935120 | 1 | rs3846055 | chr3:134203973 | CEP63 | chr3:134204575-134293852:+ | 0.25 | 4.36 | 1.7E-5 | Height |
| BLCA | cis | rs10935120 | 1 | rs3846056 | chr3:134227292 | ANAPC13 | chr3:134196547-134204865:- | 0.49 | 7.99 | 1.6E-14 | Height |
| BLCA | cis | rs10935120 | 1 | rs3846056 | chr3:134227292 | CEP63 | chr3:134204575-134293852:+ | 0.24 | 4.2 | 3.36E-5 | Height |
| BLCA | cis | rs1474698 | 1 | rs3846926 | chr6:56092186 | COL21A1 | chr6:55921389-56258892:- | 0.36 | 6.65 | 1.01E-10 | Pulse pressure |
| BLCA | cis | rs9457247 | 1 | rs385113 | chr6:167403971 | RNASET2 | chr6:167343008-167412795:- | -0.25 | -5.15 | 4.08E-7 | Crohn's disease |
| BLCA | cis | rs7714584 | 1 | rs3857422 | chr5:150268609 | LOC134466 | chr5:150310000-150326146:- | 0.47 | 6.24 | 1.17E-9 | Crohn's disease |
| BLCA | cis | rs9457247 | 1 | rs385863 | chr6:167386615 | RNASET2 | chr6:167343008-167412795:- | -0.24 | -5.04 | 7.23E-7 | Crohn's disease |
| BLCA | cis | rs9457247 | 1 | rs386548 | chr6:167385533 | RNASET2 | chr6:167343008-167412795:- | 0.25 | 5.33 | 1.66E-7 | Crohn's disease |
| BLCA | cis | rs2243480 | 1 | rs387676 | chr7:65598220 | CCT6P1 | chr7:65216092-65228661:+ | 0.34 | 4.61 | 5.54E-6 | Diabetic kidney disease |
| BLCA | cis | rs2243480 | 1 | rs3885839 | chr7:65290403 | CCT6P1 | chr7:65216092-65228661:+ | 0.33 | 4.46 | 1.08E-5 | Diabetic kidney disease |
| BLCA | cis | rs9815354 | 1 | rs3890604 | chr3:41760625 | ULK4 | chr3:41288091-42003660:- | 0.64 | 9.9 | 9.78E-21 | Diastolic blood pressure |